This plant compound has a lot to offer.

Berberine, a natural substance, has been gaining attention for its potential in treating neurodegenerative diseases like Alzheimer's, Parkinson's, and Huntington's.

Researchers have found that berberine may help limit neuroinflammation, oxidative stress and, endoplasmic reticulum stress, which can all contribute to neuron damage and cell death (Cheng Z, et.al., 2022).

The endoplasmic reticulum is a network of membranous tubules within the cell.

Inflammation and oxidative stress are factors always involved in dysfunction and diseases of the nervous system.

Research has shown that berberine can help reducing cholesterol, LDL, blood glucose and the waistline.

The research so far is promising when it comes to prevention and treatment of neurodegenerative diseases.

Reference

Ziqian Cheng, Chenglan Kang, Songtian Che1, Jingyun Su, Qihan Su, Tongtong G, Yi Guo, Jiayin Lv, Zhihui Sun, Wei Yang, Bingjin Li, Xin Li, Ranji Cui. Berberine: A Promising Treatment for Neurodegenerative Diseases. Front Pharmacol. 2022 May 20;13:845591.

 

This formula was designed to support healthy glucose, cholesterol metabolism. 

Berberine also suppresses neuroinflammatory responses through activation of the AMP-activated protein kinase (Lu DY, et al., 2010).

Berberine significantly down-regulates cyclo-oxygenase-2 (COX-2) expression in microglia cells. COX-2 are inflammatory promoting enzymes. Microglia cells are located throughout the brain and spinal cord.

It is important to keep inflammation low, especially in the brain since inflammation is one of the risk factors for memory loss.