Targets pain, especially joint pain

This is the best formula we have.

It is fast-acting and long-lasting.

Serving Size: 1 Softgel
Servings Per Container: 60

Research show effective inhibition of prostaglandin E2; one of the major pain and inflammatory producing chemicals in the body (Yamamoto K, et al. 2000. Najid A, et al. 1992. Lerman RH, et al. 2003.)

Synergy of hops extract, oleanolic acid and rosemary extract, provides high effectiveness at a low dose.

Recent research shows that components of hops may inhibit formation of prostaglandin E2 (Yamamoto K, et al. 2000.) Oleanolic acid found in plants may support the health of joints by interfering with activation of enzymes involved in the synthesis of eicosanoids [e.g. prostaglandin E2].

Carnosol and carnoic acid two components of rosemary which act as antioxidants have shown by research to help decrease the release of eicosanoids (Najid A, et al. 1992.)



References:

Lerman, R.H., Babish, J.G., Lukaczer, D., et al. Ex vivo clinical study of the anti-inflammatory activity of a proprietary synergistic blend of hops extract, rosemary and oleanolic acid. Proprietary Clinical Research Report, Gig Harbor, WA: Functional Medicine Research Center; 2003.

Najid, A., Simo, A., Cook, J., et al. Characterization of ursolic acid as a lipoxygenase and cyclooxygenase inhibitor using macrophages, plateletes and differentiated HL60 leukemic cells. FEBS Lett, 1992;299(3):213-17.

Yamamoto, K, Wang, J., Ymamoto, S., et al. Suppression of cyclooxygenase-2 gene transcription by humalon of beer hop extract studied with reference to glucorticoid. FEBS Left, 2000;465:103-6.

A proprietary blend of.....................................350 mg**
Tetrase (Tetrahydro-iso-alpha acids, from hops) (Humulus lupulus L.), Oleanolic Acid (from olive leaf extract, Olea europaea), Rosemary Leaf Extract (Rosmarinus officinalis)